Make sure your Instant Pot and seal are clean before starting.
Pour the milk into the Instant Pot, secure the lid, press the yogurt button, and press until you see the word "boil" on the screen.
When the Instant Pot makes that helpful beep, remove the lid and check the temperature with a thermometer. It should read between 180 and 200 degrees Fahrenheit.
Let the milk cool to 110 to 115 degrees Fahrenheit. This takes 1 to 2 hours on its own, or you can speed it up by setting the pot in a bowl of ice water for 10 to 15 minutes. Check the temperature often, and spoon off any skin that forms on top.
Ladle out a small amount of the warm milk into a bowl and whisk in the yogurt starter. Pour the mixture back into the pot and whisk to combine.
Place the inner pot back into the Instant Pot and secure the lid. Press the yogurt button until the screen reads 12 hours.
Once the time is up, check the yogurt. It should be thickened and jiggle just slightly.